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Product Description
Quick Detail
Product Name:Sodium Picosulfate
Synonym:4,4'-(2-Pyridinylmethylene)bis(phenol)bis(sulfuric acid sodium) salt;DA 1773;DA-1773;LA 391;C13072;Sodium Picosulfate (50 mg);Bisacodyl IMpurity D;SodiuM Picosulphate
CAS:10040-45-6
MF:C18H13NO8S2.2Na
MW:481.41
EINECS:233-120-9
Melting Point:283-286°C
Appearance: white powder
Usage: Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
Description
Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Sodipic Picofast, Laxoberal, Laxoberon, Purg-Odan, Picolax, Guttalax, Namilax, Pico-Salax and Prepopik among others. PicoPrep is based on Sodium picosulphate.
Applications
1) orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. it takes 12-24 hours to work, since it works in the colon.
2) abdominal cramps and diarrhea are normal effects of picosulfate and should be expected.
3) the use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia. patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.
4)Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
Medical Effect
1.Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12-24 hours to work, since it works in the colon.
2.The most common side effects of picosulfate are abdominal cramps and diarrhea.
3.The use of sodium picosulfate has also been associated with certainelectrolyte disturbances, such as hyponatremia and hypokalemia.[6]Patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.
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